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The Latest Biotech & Pharma Updates
Biotech & Pharma Updates | November 12 - 13, 2025
🧬 Pfizer officially closes $9.2 billion Metsera acquisition after winning bidding war against Novo Nordisk, T-Therapeutics raises $91M Series A extension to advance TCR-CD3 bispecifics for cancer/autoimmune, 4TEEN4 raises €55M ($63.75M) Series C for cardiogenic shock antibody procizumab development, Third Arc Bio + Adagene partner on cancer T cell engagers using SAFEbody technology - $5M upfront + $840M biobucks, Day One acquires struggling ADC developer Mersana for $129M upfront in milestone-heavy deal, Kura Oncology's Komzifti (ziftomenib) receives FDA approval for NPM1-mutant acute myeloid leukemia treatment
Biotech & Pharma Updates | November 11 - 12, 2025
🧬 ABL Bio + Eli Lilly partner on blood-brain barrier platform with $40M upfront + $2.562B biobucks, Indivi raises CHF15M ($18.7M) to determine precision medicine biomarkers for Alzheimer's drug development, Syrna Therapeutics emerges from stealth with covalent translation inhibitors targeting disease-causing mRNA proteins, Novartis plans approval filing for GanLum malaria drug following Ph3 success in parasitic infection treatment, Alkermes reports Ph2 success for alixorexton targeting orexin 2 receptor in narcolepsy type 2 - advancing to Ph3, Novo Nordisk slashes Wegovy weight-loss drug prices up to 33% in India amid increased competition
Biotech & Pharma Updates | November 10 - 11, 2025
🧬 Pfizer launches Ph3 trials of PF-08634404 (PD-1xVEGF bispecific) targeting non-small cell lung cancer as part of strategy to replace Keytruda, Mallinckrodt and Endo complete $6.7B merger + rebrand as Keenova and spin off Par Health generics business, Vor Bio raises $100M public offering, transforming autoimmune disease treatment, Glenmark's Ryaltris (olopatadine/mometasone furoate) wins China NMPA approval for moderate to severe allergic rhinitis treatment, UK unveils roadmap to replace animal testing with AI + 3D models
Biotech & Pharma Updates | November 9 - 10, 2025
🧬 Pfizer beats Novo Nordisk with $10B Metsera acquisition after fierce bidding war and anti-trust concerns, Eli Lilly + SanegeneBio partner on $1.2B RNAi metabolic disease platform with targeted delivery technology, Onchilles raises $25M Series A1 for dual-action cancer biologics targeting ELANE pathway
Biotech & Pharma Updates | November 5 - 6, 2025
🧬 Novo Nordisk raises Metsera bid again after Pfizer matches $10B offer in obesity drug acquisition battle, FDA approves Johnson & Johnson's Darzalex Faspro (daratumumab) for high-risk smoldering multiple myeloma following Ph3 trial, AstraZeneca acquires obesity startup SixPeaks Bio for $170M - targeting muscle-preserving weight loss drugs, Axsome acquires AstraZeneca epilepsy candidate AXS-17 through Baergic Bio acquisition (Avenue Therapeutics subsidiary) in up to $83M deal, Cencora allocates $1B over five years to expand US drug distribution with new facilities, Accipiter Biosciences launches with $12.7M Seed - developing de novo protein therapies for complex diseases, Renasant Bio launches with $54.5M seed funding to develop ADPKD small molecule treatments, Forbion closes €200M ($229.9M) BioEconomy Fund I - investing in sustainable biotechnologies
Biotech & Pharma Updates | November 4 - 5, 2025
🧬 Braveheart Bio launches with $185M to take on Bristol Myers Squibb’s heart drug in hypertrophic cardiomyopathy, Eli Lilly + XtalPi expand AI partnership to bispecific antibodies in up to $345M deal, Novo Nordisk presents Ph3 data showing oral Wegovy (semaglutide) reduces cardiovascular risk factors in obesity, FTC warns Novo Nordisk's Metsera acquisition bid may circumvent required antitrust premarket review process, AstraZeneca invests additional $136M in Chinese inhalants plant - bringing total Qingdao investment to $886M, Evommune raises $150M IPO to develop drugs for immune conditions like hives and dermatitis, Kelonia Therapeutics + Johnson & Johnson collaborate on in vivo CAR-T therapies using iGPS platform
Biotech & Pharma Updates | November 3 - 4, 2025
🧬 Novo Nordisk raises Metsera buyout bid to $10B - beating Pfizer's revised $8.1B offer, Azalea Therapeutics launches from Doudna origins with $82M and in vivo CAR-T therapy ambitions (via genome editing delivery tech), Neok Bio debuts with $75M Series A to advance bispecific ADCs targeting dual cancer markers, Hengrui Pharma + Kailera Therapeutics report positive Ph3 data for HRS9531 dual GLP-1/GIP agonist in obesity treatment, Blackstone Life Sciences signs royalty deal with Merck & Co. - paying $700M upfront in exchange for portion of sacituzumab tirumotecan future sales, Meitheal Pharmaceuticals receives FDA approval for CONTEPO (fosfomycin) targeting complicated urinary tract infections including acute pyelonephritis, Compass Pathways accelerates COMP360 commercial timeline for treatment-resistant depression following positive FDA meeting
Biotech & Pharma Updates | November 2 - 3, 2025
🧬 Eli Lilly invests $3B in Netherlands oral medicines plant + plans 500 hires for GLP-1 manufacturing expansion, AAVantgarde raises $141M Series B to advance retinal gene therapies for inherited diseases, Vertex and CRISPR Therapeutics' Casgevy shows efficacy in younger children with sickle cell disease in Ph3 trials, Roche's Gazyva (obinutuzumab) hits Ph3 primary endpoint for systemic lupus erythematosus, Neurocrine in-licenses TransThera NLRP3 inhibitors for multiple diseases for up to $881.5M, Roche + Manifold Bio partner on blood-brain barrier shuttle development - $55M upfront + $2B milestones, UCB's Kygevvi (doxecitine and doxribtimine) wins FDA approval as first therapy for thymidine kinase 2 deficiency
Biotech & Pharma Updates | October 30 - November 2, 2025
🧬 Pfizer sues Metsera + Novo Nordisk to enforce buyout deal amid obesity drug developer bidding war, Gilead seeks deals across liver + oncology + virology after $4.3B CymaBay acquisition success with Livdelzi, Maxvax Biotechnology raises $58M Series D to advance shingles and RSV vaccine trials, Arcus Biosciences raises $250M public offering for cancer/inflammatory disease drug development, Genentech's Gazyva (obinutuzumab) meets Ph3 endpoints targeting CD20 for systemic lupus erythematosus treatment, Nanobiotix receives $71M lifeline in non-dilutive capital from Healthcare Royalty, Lepu Biopharma's Vebecotamab wins Chinese NMPA approval for recurrent/metastatic nasopharyngeal carcinoma
Biotech & Pharma Updates | October 29 - 30, 2025
🧬 Novo Nordisk drops $6.5B bid for obesity drug-maker Metsera - sparking bidding war with original acquirer Pfizer, Evommune raises $159M IPO to fuel inflammation-targeting therapeutics against chronic urticaria, Eli Lilly raises revenue forecasts as obesity drug tirzepatide becomes world's best-selling medication, AstraZeneca's gefurulimab (ALXN1720) meets Ph3 endpoints for generalized myasthenia gravis, Boehringer Ingelheim in-licenses Kyowa Kirin preclinical autoimmune small molecule for up to €640M ($743M), Roche in-licenses Qyuns Therapeutics respiratory disease bispecific QX031N for $75M upfront + $995M biobucks
Biotech & Pharma Updates | October 28 - 29, 2025
🧬 Thermo Fisher to acquire Clario for $8.9B to strengthen clinical trial data capabilities, Eli Lilly + Walmart partner to expand Zepbound obesity shot access through retail pharmacy pickup, Merck & Co.'s KEYTRUDA (pembrolizumab) wins European Commission approval for resectable locally advanced head and neck squamous cell carcinoma, Roche exercises option in Recursion deal for brain immune cell genome mapping - triggering $30M payment, Sonoma Biotherapeutics reports positive Ph1 data for SBT-77-7101 CAR-Treg therapy in refractory rheumatoid arthritis, Neutrolis emerges with DNA-enzyme drug targeting immune NETs for autoimmune diseases like arthritis & lupus, Pinetree Therapeutics raises $47M Series B to develop protein degraders for drug-resistant cancers, Samsung Bioepis purchases BYOOVIZ biosimilar commercial rights in Europe from Biogen
Biotech & Pharma Updates | October 27 - 28, 2025
🧬 Eli Lilly + Nvidia partner to build pharma's “most powerful” supercomputer for drug discovery, Novartis Q3 revenue rises 8% to $13.9B as new drugs offset Entresto generic competition, Zag Bio debuts with $80M Series A to develop thymus-targeted autoimmune therapies, Bristol Myers Squibb and Cabaletta Bio's resecabtagene autoleucel CAR-T shows remissions in Ph1/2 systemic lupus erythematosus trial, Merck & Co.'s Welireg belzutifan plus Keytruda shows Ph3 success in clear cell renal cell carcinoma adjuvant treatment, Mark Cuban Cost Plus Drugs + MedChat AI partner on AI agents for online pharmacy customer support