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The Good News

THE GOOD
Approvals & Labels

Replimune's Tudriqev (RP1) wins FDA accelerated approval for advanced melanoma post-PD-1 therapy failure
Oncolytic virus, cancer, melanoma, combination therapy, PD-1, immunotherapy - Read more

TransThera Sciences' Yochanra (tinengotinib) wins China conditional approval for FGFR inhibitor-resistant cholangiocarcinoma after Ph2 success
Small molecule, cancer, kinase inhibitor, cholangiocarcinoma, FGFR2, drug resistance - Read more

THE GOOD
Business Development & Partnerships

Odyssey Therapeutics, Evotec partner on AI-driven drug discovery for autoimmune and inflammatory diseases
Research collaboration, AI/ML, autoimmune, small molecule, drug discovery, milestone payments - Read more

Rinn Pharma & Biopharma joins NordicPharmaTrain network to expand European pharmaceutical research collaboration
Research collaboration, pharmaceutical manufacturing, drug discovery, training & education - Read more

Harrow acquires TYRVAYA nasal spray for dry eye from Viatris, $30M upfront, up to $100M total
Acquisition, ophthalmology, small molecule, milestone payments, commercialization - Read more

Mediar Therapeutics, Ono Pharmaceutical collaborate on novel fibro-inflammatory disease treatments with exclusive licensing option
Research collaboration, fibrosis, autoimmune, antibody, licensing deal - Read more

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More Good News

THE GOOD
Earnings & Finances

Merck KGaA raises 2026 sales outlook to €21.8B ($25.2B), boosted by rare disease pillar from SpringWorks Therapeutics acquisition
Small molecule, rare disease, financial, major transaction - Read more

THE GOOD
Fundraises

Latigo Biotherapeutics raises $345.6M IPO to advance non-opioid pain drug pipeline
Pain, small molecule, neurological, non-opioid, clinical-stage - Read more

Vedanta Biosciences raises $60M, advancing Phase III microbiome therapy for recurrent CDI
Microbiome therapy, infectious disease, live biotherapeutic, clinical-stage - Read more

Opal Therapeutics receives $1.25M NSF investment to scale organoid platform for women's health
Organoid platform, women's health, endometriosis, preclinical, biomarker discovery - Read more

THE GOOD
Mergers & Acquisitions

Tarsus Pharmaceuticals acquires Alkeus Pharmaceuticals for up to $800M to develop Stargardt disease treatment
Small molecule, rare disease, major transaction, strategic - Read more

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The Bad News

THE BAD
Clinical Trials

Vistagen's (fasedienol) pheromone nasal spray fails to beat placebo in Ph2 social anxiety disorder study
Small molecule, neurological, nasal spray, social anxiety disorder, pherine - Read more

BioVie reports murky Ph2 results for (bezisterim) in Parkinson's disease, primary endpoint data withheld
Small molecule, neurological, Parkinson's disease, anti-inflammatory, blood-brain barrier - Read more

BioMarin Pharmaceutical scraps $270M BMN 401 program after phase 3 miss in ENPP1 deficiency
Enzyme replacement therapy, rare disease, strategic, major transaction - Read more

THE BAD
Earnings & Finances

PacBio CEO Christian Henry steps down; COO Mark Van Oene named president and CEO amid widening Q2 losses
DNA sequencing, genomics, leadership change, financial, cost reduction - Read more

THE BAD
Regulatory

Fresenius Kabi recalls mislabeled morphine lot over dilaudid mix-up risking fatal overdose
Small molecule, pain management, operational, safety - Read more

You’re all caught up on the latest Pharma & Biotech News!

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