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- Biotech & Pharma Updates | May 21 - 22, 2024
Biotech & Pharma Updates | May 21 - 22, 2024
Pfizer plans another $1.5B in cuts, biotech launches with aim to shed fat (but not muscle), Otsuka ditches an Alzheimer's med, and Novo Nordisk is on fire (again).
Welcome to the TLDR Biotech newsletter!
TLDR Biotech aims to be your one-stop source for biotech and pharma updates - all with one daily email.
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MINOR HOUSEKEEPING
How these updates are formatted
The newsletter is split into three main sections:
THE GOOD - good news (eg. fundraises, product approvals)
THE BAD - negative news (eg. clinical trial failures, layoffs)
THE UGLY - negative but atypical news (lawsuits, product recalls, scandals)
Within each of the three above parts, there are additional sections for easier navigation:
Eg. There will be multiple “The Good” sections covering things like Fundraises, Approvals, Partnerships etc.
There will be also additional tags within these sections (Eg. fundraises may mention Stage, product approvals may mention drug name and disease area.)
See something you want to get into further? Click the Read More (goes out to either a news article or a press release).
One last thing; I know paywalls can be annoying, so there’s a [Paywall] tag for any news stories behind one.
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⬇️ The Good News ⬇️
THE GOOD
Business Development
Boehringer Ingelheim pays OSE Immunotherapeutics €38.8M ($42 million) for pre-clinical asset
Antibody antagonist, cancer - Read more
Click Therapeutics clicks “buy” on assets of defunct Better Therapeutics
Digital therapeutics, obesity, diabetes - Read more
THE GOOD
Clinical Trials
Rezolute posts rezolutely positive mid-Ph2 data, boosting stock
Small molecule, eye disease, edema - Read more
Crinetics’ early share of positive mid-Ph2 data
Small molecule, congenital adrenal hyperplasia, rare disease - Read more
Sumitomo Pharma and Japan’s National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN) begin Ph1 universal influenza vaccine trial
Flu vaccine - Read more
THE GOOD
Company Launches
SixPeaks Bio launches with up to $110M, aims to cut fat but keep muscle - while AstraZeneca waits in the wings
Antibody, obesity, weight loss - Read more
THE GOOD
Criminal Acts
MilliporeSigma foils a multimillion-dollar biochemical export scheme
Biochemical product, wire fraud - Read more
THE GOOD
Fundraises
En Carta Diagnostics €1.5M ($1.6M) Pre-Seed fundraise
Diagnostics, point-of-case, Lyme disease - Read more
Captain T Cell €8.5M ($9.2M) Seed fundraise
Cell therapy, TCR-T, cancer, solid tumors - Read more
Nanopath $4M in federal funding
Diagnostics, molecular testing, women’s health - Read more
Vaxess Technologies $12M raise
Medical device, drug delivery - Read more
PolarityTE $22.5M raise
Regenerative tissue, diabetic foot ulcers - Read more
NeoPhore undisclosed Series B extension
Small molecule, neoantigen, cancer - Read more
THE GOOD
Investments
Incyte Corporations plans home-state (Delaware) expansion
Small molecule, JAK inhibitors - Read more
Asymchem takes a bite from Pfizer’s facility sandwich, takes over site
Small molecule, API, manufacturing - Read more
Daiichi Sankyo plots expansions on both sides of the pond
Research & development - Read more [Paywall]
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⬇️ The Good News (Cont.)⬇️
THE GOOD
IPOs
Tempus AI readies IPO bid
Diagnostics, AI, precision medicine - Read more
THE GOOD
Mergers & Acquisitions
Merck KGaA to buy Mirus Bio for $600M
Viral vector manufacturing - Read more
Biogen buys Hi-Bio for $1.15B upfront, $650M biobucks
Monoclonal antibody, immune-mediated indications - Read more
THE GOOD
Partnerships
AGC Biologics and BioConnection partner on end-to-end biopharma development
CDMO, manufacturing, fill-finish - Read more
THE GOOD
Patient Access
Bristol Myers Squibb maps expanded low- and middle-income country access to therapeutics
LMIC, therapeutic equity - Read more
THE GOOD
Politics & Policy
Drugmakers score win in 340B discount program limitations case - Read more [Paywall]
THE GOOD
Product Launches
Labcorp’s new preeclampsia risk blood test
Preeclampsia, diagnostic test - Read more
THE GOOD
Regulatory
FDA discusses rare disease regulatory flexibility
Rare disease, approvals - Read more [Paywall]
⬇️ The Bad News ⬇️
THE BAD
Clinical Trials
Ph3 failure means Otsuka ditches Alzheimer’s med
Small molecule, Alzheimer’s Agitation - Read more
THE BAD
Company Shutdown
Cue Health shuts down
Covid-19, diagnostic testing - Read more
THE BAD
Strategic Plans
Pfizer tacks on another $1.5B in cuts
Cost-cutting, vaccine - Read more
Evotec shutters gene therapy division
Gene therapy, viral vector, drug development - Read more
⬇️ The Ugly News ⬇️
THE UGLY
Accidents & Natural Disasters
Novo Nordisk suffers another fire, office building “unsaveable” - Read more
THE UGLY
Approvals and Labels
Novo Nordisk’s once weekly insulin’s hypoglycemia risk has FDA concerned
Diabetes, insulin, hypoglycemia - Read more [Paywall]
THE UGLY
Lawsuits
Henrietta Lacks family lawsuit against Ultragenyx moves forward
HeLa cells - Read more
THE UGLY
Politics and Policy
As BIOSECURE looms, House committee has domestic manufacturing “check up” with the FDA - Read more [Paywall]
THE UGLY
Research
New research provides more evidence linking talc powder and ovarian cancer - much to J&J’s likely chagrin
Talc powder, ovarian cancer - Read more
You’re all caught up on the latest Pharma & Biotech News!
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