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THE GOOD
Approvals & Labels

Novo Nordisk's Wegovy (targeting GLP-1) inches towards approval in India
GLP-1, obesity - Read more

Johnson & Johnson's subcutaneous Darzalex (targeting CD38) lands EC approval for newly diagnosed multiple myeloma
Monoclonal antibody, multiple myeloma, cancer, drug formulation - Read more

Johnson & Johnson's subcutaneous Rybrevant (targeting EGFRxMET) lands EC approval for advanced non-small cell lung cancer with EGFR mutations
Bispecific antibody, lung cancer, drug formulation - Read more

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THE GOOD
Clinical Trials

Rhythm Pharmaceuticals' Imcivree (MC4R agonist) delivers positive Ph3 results for acquired hypothalamic obesity
Peptide, obesity, hypothalamic obesity - Read more

Lexeo Therapeutics reports positive Ph1/2 data for LX2006 (targeting frataxin) to treat Friedreich ataxia cardiomyopathy
Gene therapy, Friedreich ataxia, adeno-associated virus (AAV) - Read more

Sonnet BioTherapeutics' SON-1010 (targeting albumin) combined with atezolizumab (targeting PD-L1) shows safety and partial response in Ph1b/2a trial for platinum-resistant ovarian cancer
Fusion protein, monoclonal antibody, ovarian cancer, combo therapy - Read more

Centessa Pharmaceuticals' ORX750 (orexin receptor agonist) delivers promising Ph1 data in narcolepsy treatment
Small molecule, narcolepsy - Read more

Verge Genomics' study shows digital biomarkers accurately track amyotrophic lateral sclerosis progression in Ph1b trial of PIKfyve inhibitor VRG50635
Amyotrophic lateral sclerosis (ALS/Lou Gehrig's disease), biomarker, AI, disease progression tracking - Read more

THE GOOD
Fundraises

Kashiv BioSciences $150M debt financing, biopharmaceutical company expanding monoclonal antibody manufacturing facilities in US and India
Monoclonal antibody, biosimilar, generic, peptide, arthritis, chronic idiopathic urticaria, asthma, chronic rhinosinusitis with nasal polyps - Read more

Caris Life Sciences $168M Growth funding, AI TechBio and precision medicine provider expanding operations and R&D sectors
AI, techbio, precision medicine, platform technology - Read more

Aelius Biotech raises £750K ($958K) investment to expand in US and Europe with laboratory gut models for drug testing without animals
Laboratory gut models, non-animal models - Read more

Signadori Bio raises funding from Invivo Partners for development of novel oncology cell therapy platform
Cell therapy, cancer - Read more

Qeen Biotechnologies receives CAD$2M ($1.48M USD) grant to develop GMP manufacturing platform for bacteriophage therapies fighting antimicrobial resistance
Bacteriophage, manufacturing platform, antibiotic resistance - Read more

THE GOOD
IPOs

DualityBio files for $200M Hong Kong IPO amid market uncertainty, banking on its ADC pipeline with major collaborations
Antibody-drug conjugate (ADC), endometrial cancer, breast cancer, solid tumor, lupus erythematosus - Read more

THE GOOD
Lawsuits

Viatris agrees to pay up to $335 million in nationwide settlement of opioid-related claims, without admitting wrongdoing
Small molecule, opioid, opioid epidemic - Read more

THE GOOD
Partnerships

GSK, ABL Bio worldwide partnership to develop neurodegenerative disease treatments using ABL's blood-brain barrier shuttle platform
Antisense oligonucleotide, siRNA, antibody, oligonucleotide, cancer, neurodegenerative disease, drug delivery, bispecific antibody, blood-brain barrier, drug development - Read more

Google, Ai2 each commit $10M to Cancer AI Alliance for accelerating cancer research with AI technology
AI, cancer, Research & Development - Read more

THE GOOD
Politics & Policy

Federal judge permanently blocks Trump-era cuts to university research overhead payments, ruling the policy violated federal law
Federal research funding - Read more [Paywall]

BioMed X launches XBridge Program to connect threatened NIH grants with pharmaceutical industry funding partners
National Institute of Health (NIH), public funding, public-private partnership - Read more

US government announces 5.06% Medicare Advantage payment increase for 2026, boosting health insurer stocks amid high costs
Medicare Advantage, health insurance - Read more

THE GOOD
Product Launches

AccuStem launches blood test in US to improve lung cancer screening accuracy by identifying malignant nodules
Blood test, diagnostics, lung cancer - Read more

THE GOOD
Research

UC Berkeley and UCSF researchers develop fast brain-computer interface for paralyzed people to speak naturally through thoughts
Brain-computer interface, thought-to-speech, medical device - Read more [Paywall]

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THE BAD
Company Shutdown

AmplifyBio shuts down after failed attempts to secure funding amid declining market for early-stage cell and gene therapies
CDMO (Contract Development & Manufacturing Organization), cell therapy, gene therapy, cell therapy manufacturing, gene therapy manufacturing - Read more

THE BAD
Lawsuits

Judge dismisses AbbVie and AstraZeneca's challenge to Minnesota's 340B law, ruling it lacks enforcement mechanisms
340B Drug Pricing Program - Read more [Paywall]

THE BAD
Layoffs

Lyell Immunopharma closing Los Angeles site, laying off 73 employees, and relocating IMPT-314 manufacturing to Washington state
Cell therapy, CAR-T, lymphoma, cancer - Read more

THE BAD
Market Reports

Trump's tariffs on pharmaceutical tools and packaging production expected to impact drug makers through increased costs
Pharmaceutical packaging, tariffs, autoinjector manufacturing - Read more

THE BAD
Mergers & Acquisitions

Nordic Capital announces it will not make an offer for PureTech Health after initial proposal was rejected
Small molecule, fibrosis-driven disease, inflammatory disease, cancer - Read more

THE BAD
Research

iBio's IBIO-600 showed promising muscle growth in animal study, but lacked statistical significance with single-dose administration
Antibody, obesity, cardiometabolic disease - Read more

THE UGLY
Lawsuits

Eli Lilly sues Indianapolis spa Premier Weight Loss for illegally repacking and selling Zepbound weight-loss injections for profit
GLP-1, obesity, compounding, trademark infringement - Read more

THE UGLY
Politics & Policy

Trump's tariffs trigger market downturn, hitting biotech industry already struggling with interest rates and inflation; companies face cuts
Tariffs, biotech ecosystem - Read more

CDC shuts top STD lab, firing all 28 staff amid global concerns over antibiotic-resistant gonorrhea surveillance
Centers for Disease Control and Prevention (CDC), sexually transmitted diseases, public agency layoffs - Read more [Paywall]

Trump's CDC budget cuts threaten crucial HIV prevention programs and progress made over 40 years
Human immunodeficiency virus (HIV), federal research funding, public agency layoffs, Centers for Disease Control and Prevention (CDC) - Read more [Paywall]

THE UGLY
Public Health

Unvaccinated child with measles dies in Texas, the second death amid an outbreak affecting nearly 500 people statewide
Measles, infectious disease, infectious disease outbreak - Read more

You’re all caught up on the latest Pharma & Biotech News!

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