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THE GOOD
Approvals & Labels

Galderma lands FDA approval for chronic skin condition antibody (Nemluvio)
Monoclonal antibody, prurigo nodularis, dermatology - Read more

AstraZeneca, Daiichi Sankyo’s Enhertu nabs conditional approval for third indication in China
Monoclonal antibody, gastric or gastroesophageal junction adenocarcinoma, cancer - Read more

THE GOOD
Business Development

Evotec nabs $75M after achieving milestone in Bristol Myers Squibb strategic partnership
Small molecule, molecular glue, drug discovery & development - Read more

Prolific Machines receives grant from Bill & Melinda Gates Foundation to develop mAbs manufacturing platform for low- and middle-income countries
Monoclonal antibody, drug manufacturing, biomanufacturing - Read more

Biden administration grants Tulane University $23M for cancer detection tech development
Cancer Moonshoot, cancer detection - Read more

Baxter sells kidney care division to PE firm Carlyle Group for $3.8B
Medical device, renal therapy, dialysis - Read more

THE GOOD
Clinical Trials

Despite Lykos MDMA flop, the space ain’t dead as atai Life Sciences posts positive preliminary data from Ph1b DMT formulation (VLS-01)
Small molecule, psychedelic, treatment-resistant depression - Read more

Rivus Pharmaceuticals obesity-related heart failure med (that spares muscle mass) hits Ph2a primary endpoint (HU6)
Small molecule, obesity-related heart failure - Read more

Lynk Pharmaceuticals lynks atopic dermatitis hopeful with positive safety profile in Ph1b trial (LNK01004)
Small molecule, atopic dermatitis - Read more

THIS IS POSITIVE results for Apollomics’ Ph2 SPARTA trial in non-CNS MET fusion solid tumors (vebreltinib)
Small molecule, solid tumor - Read more

Kyverna Therapeutics reports positive initial safety data for their CAR-T autoimmune play (KYV-101)
CAR-T cell therapy, autoimmune - Read more

Cybin aims to overcome Lykos Therapeutics’ functional unblinding misstep with upcoming Ph3 clinical trial (CYB003)
Small molecule, psychedelic, major depressive disorder - Read more

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⬇️ The Good News (Cont’d) ⬇️

THE GOOD
Company Launches

Create Health Ventures launches with first $21M fund, aimed at investing in tech that improves patient access to care
Patient access, digital health - Read more

THE GOOD
Fundraises

Australian biotech incubator Proto Axiom closes $20M of $30M Series B
Biotech incubation, company creation - Read more

Pelage Pharmaceuticals $14M Series A-1
Small molecule, hair loss, androgenetic alopecia, chemotherapy-induced-alopecia - Read more

THE GOOD
Investments

Eli Lilly open $700M Boston R&D site*
Nucleic acid, research & development - Read more
*you won’t be able to unsee it

THE GOOD
Lawsuits

Competition is a good thing, as Novartis takes another L in Entresto generics lawsuit saga
Small molecule, heart failure, generic - Read more

THE GOOD
Opinions

50% of surveyed healthcare professionals consider DTC pharma ads “somewhat” or “extremely” helpful
Direct-to-consumer pharma advertising, pharma marketing - Read more 

THE GOOD
Partnerships

Astria Therapeutics partners with Ypsomed for their injection device for Astria’s STAR-0215 delivery
Monoclonal antibody, hereditary angioedema, medical device - Read more

Adial Pharmaceuticals partners with Boudicca Dx on companion diagnostic genetic test for AD04
Small molecule, alcohol use disorder - Read more

THE GOOD
Politics & Policy

IRA drug price negotiation report to release Thursday
Inflation reduction act, drug pricing - Read more [Paywall]

THE GOOD
Regulatory

FDA adcomm participants weigh in on adcomm changes
Advisory committee - Read more [Paywall]

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THE BAD
Clinical Trals

Ovid Therapeutics cuts preclinical work on OV329 IV formulation
Small molecule, epilepsy, seizure disorder - Read more

Syros Pharmaceuticals halts further enrolment in Ph2 leukemia trial (tamibarotene)
Small molecule, leukemia, cancer - Read more

THE BAD
Earnings & Finances

CSL Behring isn’t super jazzed about slower-than-expected Hemgenix sales
Gene therapy, hemophilia B - Read more [Paywall]

Activist investor takes on Aurinia Pharma as internal turmoil persists
Small molecule, fusion protein, autoimmune - Read more

Mersana Therapeutics underperforms (financially) in Q2
Antibody-drug conjugate, cancer - Read more

THE BAD
IPOs

Actuate Therapeutics’ underwhelming $22M IPO (when they were aiming for $50M)
Small molecule, pancreatic cancer - Read more

THE BAD
Layoffs

Boundless Bio conducts “modest” layoffs, 15 employees (20% of workforce)
Extrachromosomal DNA, cancer - Read more

Lexicon Pharmaceuticals cuts workforce in half, 75 employees
Small molecule, heart failure, type 1 diabetes, chronic kidney disease - Read more

Acelyrin shelves clinical asset and cuts 1/3rd of workforce, 43 employees
Fusion protein, hidradenitis suppurativa, psoriatic arthritis, autoimmune - Read more

THE UGLY
Politics & Policy

Prasco, GSK are allegedly overcharging for generic version of pediatric inhaler, Senator Bernie Sanders urges price cap
Small molecule, asthma, chronic obstructive pulmonary disease (COPD), drug pricing - Read more

You’re all caught up on the latest Pharma & Biotech News!

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