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The Good News

THE GOOD
Approvals & Labels

Boehringer Ingelheim's Hernexeos (zongertinib) wins FDA accelerated approval for front-line HER2-mutated non-small-cell lung cancer
Small molecule, cancer, tyrosine kinase inhibitor, non-small cell lung cancer, HER2 - Read more

THE GOOD
Business Development & Partnerships

Boehringer Ingelheim, Sitryx Therapeutics partner on autoimmune oral drugs, potentially worth $500M+
Licensing deal, autoimmune, small molecule, milestone payments - Read more

Emergent BioSolutions secures approximately $140M CAD ($102.3M) in Canadian government contracts for medical countermeasures
Government contract, biodefense, manufacturing agreement, medical countermeasures - Read more

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More Good News

THE GOOD
Clinical Trials

argenx's Vyvgart (efgartigimod alfa) meets Ph3 primary endpoint for ocular myasthenia gravis treatment
Antibody, autoimmune, antibody fragment, myasthenia gravis, IgG targeting, subcutaneous - Read more

AtaiBeckley's EMP-01 (R-MDMA) shows positive Ph2a results for social anxiety disorder treatment
Small molecule, neurological, MDMA, social anxiety disorder, psychedelic therapy - Read more

SolasCure's Aurase Wound Gel (tarumase) shows faster healing in chronic venous leg ulcers Ph2 trial
Protein therapy, dermatological, enzymatic debridement, chronic venous leg ulcers, tarumase, PAR2 receptors - Read more

Bristol Myers Squibb's iza-bren shows survival benefit in Ph3 trial for triple-negative breast cancer
Antibody drug conjugate, cancer, triple-negative breast cancer, EGFR target, HER3 target - Read more

Eli Lilly's orforglipron (GLP-1) outperforms Novo's Rybelsus in Ph3 diabetes trial on weight loss and blood sugar
Small molecule, metabolic, GLP-1 receptor agonist, type 2 diabetes, obesity, oral medication - Read more

MindRank doses first patient in Ph3 trial for MDR-001 oral GLP-1 receptor agonist targeting overweight or obesity
Small molecule, metabolic, GLP-1 receptor agonist, obesity, AI drug design - Read more

Bayer's Xofigo (radium-223 dichloride) plus enzalutamide shows 24% survival benefit in Ph3 metastatic castration-resistant prostate cancer trial
Radiopharmaceutical, cancer, radium-223, metastatic castration-resistant prostate cancer, combination therapy, bone metastases - Read more

THE GOOD
Fundraises

Generate Biomedicines raises $400M IPO, AI drug discovery specialist developing asthma treatments
AI/ML platform, drug discovery, autoimmune, clinical-stage - Read more

Metagen Therapeutics raises ¥3.52B ($22.5M) Series B for microbiota drug development
Microbiota therapeutics, ulcerative colitis, fecal microbiota transplantation, clinical-stage - Read more

THE GOOD
Mergers & Acquisitions

Asahi Kasei acquires Germany's Aicuris for $920M to boost viral infection R&D portfolio
Antiviral, infectious disease, strategic, major transaction - Read more

THE GOOD
Product Launches

Walgreens launches Weight Management GLP-1 programme with virtual healthcare platform
GLP-1 receptor agonist, obesity, strategic, operational - Read more

THE GOOD
Strategic Plans

Protagonist Therapeutics plans to opt out of Takeda rusfertide profit-sharing for $400M payments
Licensing deal, rare disease, small molecule, milestone payments, royalties - Read more

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The Bad News

THE BAD
Layoffs

Viatris to cut 10% of workforce in 3-year restructuring, reports fire at India manufacturing plant
Generic drugs, operational, cost reduction, financial - Read more

THE BAD
Regulatory

Senate hearing criticizes FDA's rare disease review process following Biohaven's troriluzole rejection for spinocerebellar ataxia
Small molecule, neurological, regulatory, rare disease - Read more

CDC vaccine panel schedules March meeting to discuss COVID-19 vaccine safety and long COVID issues
mRNA vaccine, infectious disease, regulatory, operational - Read more

👹 The Ugly News 👹

THE UGLY
No Ugly News Today!

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