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THE GOOD
Business Development & Partnerships

Roche, MediLink partner on B7H3-targeted ADC YL201, $570M upfront and near-term milestones
Licensing deal, oncology, antibody-drug conjugate, milestone payments - Read more

Pierre Fabre Laboratories, Iktos collaborate on AI-driven oncology drug discovery with undisclosed upfront, milestone payments
Research collaboration, oncology, AI/ML, small molecule, milestone payments - Read more

Eli Lilly, Chai Discovery partner on AI drug design using Chai 1 and Chai 2 platforms
Research collaboration, AI/ML, drug discovery, small molecule, antibody - Read more

Teva Pharmaceuticals, Royalty Pharma enter $500M funding agreement to accelerate TEV-'408 vitiligo treatment development
R&D funding agreement, autoimmune, antibody, milestone payments, royalties - Read more

Genentech switches to Rightway pharmacy benefit manager, expects $70M savings through 2028
Service agreement, cost reduction, digital health - Read more [Paywall]

Madrigal, Pfizer license MASH drug ervogastat for $50M upfront plus milestones
Licensing deal, MASH, small molecule, milestone payments - Read more

PRESENTED BY SCIENCE 2 SALES
Cold calling in the life sciences - free webinar!

By popular demand, we’re running two webinars on cold calling in the life sciences - our first one was a hit, and there’s one more TOMORROW!

We’ll be covering:
• Why cold calling is so powerful right now (hint: points at all the AI everywhere)
• What is (and isn't) cold calling
• When it's worth it (sometimes it's not!)
• Mindset, strategies, and the technical bits behind doing cold calling

And probably a bunch more things - also a special guest 👀

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✅ More Good News ✅

THE GOOD
Clinical Trials

Sustained Therapeutics reports positive Ph2 results for ST-01 targeting chronic scrotal pain
Small molecule, chronic pain, sustained-release, non-opioid, chronic scrotal pain - Read more

Krystal Biotech reports positive Ph1 interim results for KB407 confirming wild-type CFTR delivery in cystic fibrosis patients
Gene therapy, respiratory disease, adeno-associated virus, cystic fibrosis, CFTR protein, inhaled delivery - Read more

Enliven Therapeutics reports 69% response rate for ELVN-001 tyrosine kinase inhibitor in chronic myeloid leukemia Ph1 trial
Small molecule, cancer, tyrosine kinase inhibitor, chronic myeloid leukemia, HER2 inhibitor - Read more

THE GOOD
Company Launches

Aurora Therapeutics debuts with $16M seed funding to develop multiple gene therapies using FDA's new regulatory pathway
Gene editing, rare disease, strategic, investment - Read more

Topos Bio emerges from stealth with $10.5M seed funding to target undruggable Alzheimer's and cancer proteins
Small molecule, neurological, financial, strategic - Read more

AirNexis Therapeutics debuts with $200M series A funding to develop China-sourced COPD therapy AN01
Small molecule, respiratory, strategic, major transaction - Read more

THE GOOD
Earnings & Finances

Insmed reports blowout $144.6M Q4 sales for bronchiectasis drug Brinsupri, tripling analyst expectations
Inhaled therapy, respiratory, financial, revenue impact, major transaction - Read more

THE GOOD
Fundraises

Orca Bio raises $250M Series F, cell therapy commercialization and pipeline advancement
Cell therapy, blood cancer, allogeneic immunotherapy, clinical-stage - Read more

Eikon Therapeutics files IPO, immuno-responsive cancer treatments including TLR7/8 dual-agonist
Oncology, small molecule, clinical-stage, immuno-responsive cancers - Read more

MEDIPOST Inc. raises $140M funding, umbilical cord blood-derived stem cell therapies
Cell therapy, regenerative medicine, clinical-stage, umbilical cord blood - Read more

Veradermics raises $100M IPO, developing oral minoxidil for hair loss
Dermatology, clinical-stage, small molecule, hair loss - Read more

Kinaset Therapeutics raises $103M Series B, inhaled therapeutic for respiratory diseases
Respiratory diseases, small molecule, clinical-stage, inhaled therapeutics - Read more

UPenn, BioNTech, Osage launch $50M seed fund for Penn life science startups
Venture fund, early-stage, therapeutics, diagnostics, AI-enabled drug discovery - Read more

a16z raises $700M Bio + Health fund for biotech and healthtech investments
Venture capital, biotech investment, healthtech investment, AI-driven - Read more

Ribo Life Science raises $230M IPO, siRNA therapies for cardiometabolic diseases
siRNA, clinical-stage, cardiometabolic, renal disease - Read more

Mirador Therapeutics raises $250M Series B, developing precision medicines for immune diseases
Immunology, precision medicine, clinical-stage, autoimmune - Read more

THE GOOD
Investments

Novartis to build fourth US radioligand therapy manufacturing facility in Florida as part of $23B investment
Radioligand therapy, oncology, strategic, major investment, operational, manufacturing expansion - Read more

THE GOOD
Mergers & Acquisitions

Merck & Co. reportedly in talks to acquire Revolution Medicines for $28-32B amid competing buyout rumors
Small molecule, oncology, strategic, major transaction - Read more

THE GOOD
Politics & Policy

J&J joins Trump Administration's MFN pricing deal, adds TrumpRx platform for discounted medicines
Cell therapy, pricing strategy, manufacturing expansion, tariff exemption - Read more

THE GOOD
Regulatory

FDA eases CMC requirements for cell and gene therapies to accelerate development while maintaining quality standards
Cell therapy, gene therapy, regulatory, operational - Read more

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THE BAD
Company Shutdown

Rampart Bioscience closes less than 2 years after launching with $85M DNA therapy platform
Gene therapy, rare disease, operational, financial - Read more

THE UGLY
No Ugly News Today!

You’re all caught up on the latest Pharma & Biotech News!

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