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The Good News

THE GOOD
Approvals & Labels

NICE recommends AbbVie's Aquipta (atogepant) for acute migraine with or without aura following Ph3 data
Small molecule, neurological, CGRP receptor antagonist, migraine, gepant - Read more

FDA approves Eli Lilly's EBGLYSS (lebrikizumab-lbkz) every-eight-week maintenance dosing for moderate-to-severe atopic dermatitis
Antibody, autoimmune, monoclonal antibody, atopic dermatitis, IL-13 inhibitor, lebrikizumab - Read more

THE GOOD
Business Development & Partnerships

Novartis, Orionis Biosciences expand molecular glue collaboration with $40M upfront, up to $1.4B milestones
Research collaboration, small molecule, molecular glue, AI/ML, milestone payments, oncology - Read more

IBA, MD Anderson Cancer Center collaborate on proton therapy health economics and cost-effectiveness evidence generation
Research collaboration, oncology, health economics, radiation therapy, data analytics - Read more

Cartesian Therapeutics, WestGene Biopharma license in vivo CAR-T platform for autoimmune diseases development
Licensing deal, autoimmune, cell therapy, mRNA, milestone payments - Read more

AmMax Bio licenses Lonza's SYNtecan ADC platform for hematological cancer treatment AMB-104, milestones and royalties eligible
Licensing deal, oncology, antibody-drug conjugate, milestone payments, royalties - Read more

Sofinnova Partners, AWS collaborate to scale AI-powered life sciences innovation through Sofia platform
Research collaboration, AI/ML, drug discovery, venture capital, digital health - Read more

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More Good News

THE GOOD
Company Launches

Ethyreal Bio launches with $101M to advance ETHY-001, a precision therapy targeting Graves’ disease and thyroid eye disease
Autoimmune, antibody, thyroid disease, preclinical - Read more

THE GOOD
Fundraises

Parabilis Medicines raises $670M IPO, largest-ever biotech debut for cancer drug developer
Oncology, peptide therapy, platform technology, rare disease, clinical-stage - Read more

SonoThera raises $125M Series B, advancing bubble-based genetic medicine delivery platform
Gene therapy, rare disease, ultrasound delivery, Duchenne muscular dystrophy, clinical-stage - Read more

Idorsia secures up to $313M loan from Pharmakon Advisors, extending cash runway into 2028
Specialty pharma, small molecule, cardiovascular, clinical-stage - Read more

Shattuck Labs prices $75M public offering, advancing DR3 blocking antibodies for inflammatory diseases
Clinical-stage, antibody, autoimmune, bispecific - Read more

Tango Therapeutics prices upsized $600M public offering for precision cancer medicines development
Clinical-stage, oncology, precision medicine, small molecule - Read more

Summit Therapeutics plans $500M public offering to fund ivonescimab R&D and general corporate purposes
Oncology, clinical-stage, antibody - Read more

Element Biosciences raises over $175M Series E, advancing DNA sequencing and multi-omics technologies
Genomics, DNA sequencing, multi-omics, platform technology, precision medicine - Read more

THE GOOD
Mergers & Acquisitions

Galmed Pharmaceuticals acquires Colospan for $4.5M, targeting $6B gastrointestinal diagnostics market
Medical device, gastrointestinal, major transaction, strategic - Read more

THE GOOD
Politics & Policy

NIH appoints John Powers III as acting NIAID director amid ongoing leadership vacuum
Infectious disease, leadership, operational - Read more

THE GOOD
Regulatory

Disc Medicine reaches FDA agreement to resubmit (bitopertin) via Ph3 trial for erythropoietic protoporphyria
Small molecule, rare blood disease, glycine transporter 1 inhibitor, erythropoietic protoporphyria, oral therapy - Read more

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The Bad News

THE BAD
Clinical Trials

Sanofi discontinues Ph3 MOBILIZE trial of (riliprubart) in chronic inflammatory demyelinating polyneuropathy due to insufficient efficacy
Antibody, autoimmune, complement inhibitor, chronic inflammatory demyelinating polyneuropathy, monoclonal antibody - Read more

THE BAD
Layoffs

Teva Pharmaceuticals cuts 250 jobs at TAPI unit amid prolonged search for division buyer
Active pharmaceutical ingredients, operational, cost reduction, divestiture - Read more

👹 The Ugly News 👹

THE UGLY
Politics & Policy

WuXi AppTec added to Pentagon's Chinese military companies list, triggering automatic Biosecure Act restrictions
CDMO services, biosecurity, regulatory, competitive - Read more

You’re all caught up on the latest Pharma & Biotech News!

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