
Parabilis Medicines raises $670M IPO, largest-ever biotech debut for cancer drug developer | Gif: curbyourenthusiasm on Giphy
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✅ The Good News ✅
THE GOOD
Approvals & Labels
NICE recommends AbbVie's Aquipta (atogepant) for acute migraine with or without aura following Ph3 data
Small molecule, neurological, CGRP receptor antagonist, migraine, gepant - Read more
FDA approves Eli Lilly's EBGLYSS (lebrikizumab-lbkz) every-eight-week maintenance dosing for moderate-to-severe atopic dermatitis
Antibody, autoimmune, monoclonal antibody, atopic dermatitis, IL-13 inhibitor, lebrikizumab - Read more
THE GOOD
Business Development & Partnerships
Novartis, Orionis Biosciences expand molecular glue collaboration with $40M upfront, up to $1.4B milestones
Research collaboration, small molecule, molecular glue, AI/ML, milestone payments, oncology - Read more
IBA, MD Anderson Cancer Center collaborate on proton therapy health economics and cost-effectiveness evidence generation
Research collaboration, oncology, health economics, radiation therapy, data analytics - Read more
Cartesian Therapeutics, WestGene Biopharma license in vivo CAR-T platform for autoimmune diseases development
Licensing deal, autoimmune, cell therapy, mRNA, milestone payments - Read more
AmMax Bio licenses Lonza's SYNtecan ADC platform for hematological cancer treatment AMB-104, milestones and royalties eligible
Licensing deal, oncology, antibody-drug conjugate, milestone payments, royalties - Read more
Sofinnova Partners, AWS collaborate to scale AI-powered life sciences innovation through Sofia platform
Research collaboration, AI/ML, drug discovery, venture capital, digital health - Read more
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✅ More Good News ✅
THE GOOD
Company Launches
Ethyreal Bio launches with $101M to advance ETHY-001, a precision therapy targeting Graves’ disease and thyroid eye disease
Autoimmune, antibody, thyroid disease, preclinical - Read more
THE GOOD
Fundraises
Parabilis Medicines raises $670M IPO, largest-ever biotech debut for cancer drug developer
Oncology, peptide therapy, platform technology, rare disease, clinical-stage - Read more
SonoThera raises $125M Series B, advancing bubble-based genetic medicine delivery platform
Gene therapy, rare disease, ultrasound delivery, Duchenne muscular dystrophy, clinical-stage - Read more
Idorsia secures up to $313M loan from Pharmakon Advisors, extending cash runway into 2028
Specialty pharma, small molecule, cardiovascular, clinical-stage - Read more
Shattuck Labs prices $75M public offering, advancing DR3 blocking antibodies for inflammatory diseases
Clinical-stage, antibody, autoimmune, bispecific - Read more
Tango Therapeutics prices upsized $600M public offering for precision cancer medicines development
Clinical-stage, oncology, precision medicine, small molecule - Read more
Summit Therapeutics plans $500M public offering to fund ivonescimab R&D and general corporate purposes
Oncology, clinical-stage, antibody - Read more
Element Biosciences raises over $175M Series E, advancing DNA sequencing and multi-omics technologies
Genomics, DNA sequencing, multi-omics, platform technology, precision medicine - Read more
THE GOOD
Mergers & Acquisitions
Galmed Pharmaceuticals acquires Colospan for $4.5M, targeting $6B gastrointestinal diagnostics market
Medical device, gastrointestinal, major transaction, strategic - Read more
THE GOOD
Politics & Policy
NIH appoints John Powers III as acting NIAID director amid ongoing leadership vacuum
Infectious disease, leadership, operational - Read more
THE GOOD
Regulatory
Disc Medicine reaches FDA agreement to resubmit (bitopertin) via Ph3 trial for erythropoietic protoporphyria
Small molecule, rare blood disease, glycine transporter 1 inhibitor, erythropoietic protoporphyria, oral therapy - Read more
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❌ The Bad News ❌
THE BAD
Clinical Trials
Sanofi discontinues Ph3 MOBILIZE trial of (riliprubart) in chronic inflammatory demyelinating polyneuropathy due to insufficient efficacy
Antibody, autoimmune, complement inhibitor, chronic inflammatory demyelinating polyneuropathy, monoclonal antibody - Read more
THE BAD
Layoffs
Teva Pharmaceuticals cuts 250 jobs at TAPI unit amid prolonged search for division buyer
Active pharmaceutical ingredients, operational, cost reduction, divestiture - Read more
👹 The Ugly News 👹
THE UGLY
Politics & Policy
WuXi AppTec added to Pentagon's Chinese military companies list, triggering automatic Biosecure Act restrictions
CDMO services, biosecurity, regulatory, competitive - Read more
You’re all caught up on the latest Pharma & Biotech News!
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