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The Good News

THE GOOD
Approvals & Labels

JenaValve's Trilogy valve wins first FDA approval for severe aortic regurgitation treatment
Medical device, cardiovascular, transcatheter aortic valve replacement, aortic regurgitation, minimally invasive surgery - Read more

Johnson & Johnson's Icotyde (icotrokinra) wins FDA approval for moderate-to-severe plaque psoriasis targeting interleukin-23
Small molecule, autoimmune, psoriasis, IL-23 inhibitor, oral therapy - Read more

THE GOOD
Business Development & Partnerships

Samsung Bioepis, Sandoz partner on five next-generation biosimilars including SB36 vedolizumab biosimilar
Commercialization partnership, autoimmune, biosimilars, manufacturing agreement - Read more

Nautilus Biotechnology, Baylor College of Medicine partner on cancer proteomics research using Voyager Platform
Research collaboration, oncology, proteomics, single-molecule analysis - Read more

Elaris, Valneva partner on exclusive global license for C. difficile vaccine technology with milestone payments
Licensing deal, infectious disease, vaccine, milestone payments - Read more

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More Good News

THE GOOD
Clinical Trials

Aspen Neuroscience plans Ph3 trial for sasineprocel (ANPD001) cell therapy targeting Parkinson's disease following positive Ph1/2a data
Cell therapy, neurological, induced pluripotent stem cells, Parkinson's disease, dopaminergic neurons - Read more

Stoke Therapeutics reports Ph1/2 results for zorevunersen targeting SCN1A gene in Dravet syndrome treatment
Antisense oligonucleotide, neurological, Dravet syndrome, SCN1A gene, NaV1.1 protein - Read more

Sobi presents positive Ph2a results for Gamifant (emapalumab) targeting interferon-gamma in sepsis patients
Antibody, infectious disease, monoclonal antibody, sepsis, interferon-gamma target, precision medicine - Read more

THE GOOD
Fundraises

Imperative Care nets $100M convertible financing, stroke treatment hardware developer
Neurological, medical devices, stroke treatment, robotic platform - Read more

Crossbow Therapeutics raises $77M Series B, developing next-generation cancer immunotherapies
Cancer, T cell engager, immunotherapy, clinical-stage - Read more

Excalipoint Therapeutics raises $68.7M seed, developing next-gen T cell cancer immunotherapies
Oncology, antibody, T cell engager, tri-specific antibody, clinical-stage, platform technology - Read more

Ovid Therapeutics raises $60M PIPE financing for brain disorder drug development
Neurological, small molecule, brain disorders, clinical-stage - Read more

Reviva Pharmaceuticals raises $10M public offering, late-stage CNS/inflammatory disease therapies
Central nervous system, late-stage, inflammatory, cardiometabolic - Read more

Kupando raises additional €10M ($11.5M) Series A for cancer, infectious disease therapies
Cancer, infectious disease, clinical-stage, platform technology - Read more

THE GOOD
Investments

TerraPower commits $450M to build Philadelphia radioisotope production plant, boosting actinium-225 capacity 20-fold
Radioisotope, oncology, strategic, major transaction, operational - Read more

THE GOOD
Regulatory

FDA releases draft guidance framework for drugmakers to replace animal testing with alternative methodologies
Drug development methodologies, regulatory, operational, strategic - Read more

THE GOOD
Strategic Plans

Basecamp Research unveils Trillion Gene Atlas plan to sequence trillion proteins within two years
AI drug discovery, strategic, operational, major transaction - Read more [Paywall]

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The Bad News

THE BAD
Earnings & Finances

HSBC downgrades Eli Lilly stock citing obesity market pricing pressures and orforglipron competition concerns
GLP-1 agonist, obesity, financial, competitive, strategic - Read more

THE BAD
Politics & Policy

TrumpRx's "world's lowest" drug price claims challenged by NYT finding cheaper German prices
Small molecule, multiple therapeutic areas, cost reduction, competitive, operational - Read more

👹 The Ugly News 👹

THE UGLY
No Ugly News Today!

You’re all caught up on the latest Pharma & Biotech News!

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