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The Good News

THE GOOD
Approvals & Labels

Sanofi and Regeneron's Dupixent (dupilumab) wins Japan approval for bullous pemphigoid following Ph2/3 success
Antibody, autoimmune, monoclonal antibody, bullous pemphigoid, IL-4 receptor antagonist, dupilumab - Read more

THE GOOD
Business Development & Partnerships

Merck & Co., Quotient Therapeutics partner on IBD drug discovery, $20M upfront, $2.2B milestones
Research collaboration, autoimmune, drug discovery, milestone payments - Read more

Icon, Advarra partner to launch connected clinical trial site network using AI platform
Research collaboration, clinical trials, AI/ML, digital health - Read more

Shionogi buys out Apnimed's stake in sleep-focused joint venture for $100M
Acquisition, sleep disorders, small molecule, milestone payments - Read more

Gilead, Manta Cares partner to distribute lung and breast cancer patient navigation tools nationwide
Patient support collaboration, oncology, digital health, antibody-drug conjugate - Read more

Alnylam, Viz.ai partner on cardiac amyloidosis care pathway for earlier diagnosis, financial terms undisclosed
Research collaboration, AI/ML, diagnostics, rare disease - Read more

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More Good News

THE GOOD
Clinical Trials

Ocugen advances OCU410 gene therapy targeting RORA to Ph3 for geographic atrophy following positive Ph2 results
Gene therapy, ophthalmology, AAV vector, geographic atrophy, age-related macular degeneration, RORA target - Read more

Karyopharm Therapeutics' Xpovio meets primary endpoint in Ph3 myelofibrosis trial, mixed secondary results
Small molecule, blood disorders, XPO1 inhibitor, myelofibrosis, combination therapy, spleen volume reduction - Read more

THE GOOD
Company Launches

Clockwork Bio launches as AI-native drug discovery platform targeting oncology with autonomous cell state control
AI-based drug discovery, oncology, strategic, operational - Read more

THE GOOD
Fundraises

Immutrin raises $87M Series A, antibody therapy for progressive heart disease
Cardiovascular, antibody, rare disease, clinical-stage - Read more

Karyopharm Therapeutics raises $30M private placement for cancer therapy clinical trials
Oncology, small molecule, clinical-stage, commercial-stage - Read more

Gilgamesh Pharma raises $60M Series A, developing neuropsychiatric therapies for psychiatric disorders
Neuropsychiatric, small molecule, clinical-stage, NMDA receptor - Read more

RyboDyn raises $10M Seed funding, AI-powered platform for cancer immunotherapy discovery
Cancer, AI/ML platform, antibody, platform technology, biomarker discovery - Read more

EpiFrontier Therapeutics raises $32M grant funding for beta globin disorder therapies
Rare disease, small molecule, clinical-stage, G9a inhibition - Read more

THE GOOD
Investments

UCB to build $2B biologics manufacturing facility near Atlanta headquarters, creating 330 jobs
Biologics, strategic, major transaction, operational - Read more

Wilmington PharmaTech commits $50M to double Delaware API manufacturing capacity by Q3 2027
Small molecule, strategic, major transaction, operational, manufacturing expansion - Read more

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The Bad News

THE BAD
Clinical Trials

Aardvark pauses 2 obesity trials, reveals new details on cardiac concerns
Small molecule, metabolic, obesity, GLP-1 receptor, cardiac safety, combination therapy - Read more

THE BAD
Regulatory

FDA issues warning letter to ImmunityBio over false, misleading Anktiva cancer drug promotional claims
Immunotherapy, oncology, regulatory, operational - Read more

THE BAD
Strategic Plans

Eli Lilly to discontinue multiple insulin products across European markets by 2027 for commercial reasons
Insulin, diabetes, strategic, operational - Read more

👹 The Ugly News 👹

THE UGLY
Lawsuits

SCOTUS allows RICO class action against Takeda and Eli Lilly over Actos diabetes drug to proceed
Small molecule, diabetes, financial, major transaction, competitive - Read more

THE UGLY
Regulatory

Strides Pharma recalls 90K children's ibuprofen bottles after contamination complaints include gel-like mass, black particles
Small molecule, regulatory, operational, quality control - Read more

You’re all caught up on the latest Pharma & Biotech News!

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