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Eli Lilly, XtalPi expand AI partnership to bispecific antibodies, $345M potential deal value
Research collaboration, AI/ML, bispecific antibodies, milestone payments - Read more

Dynavax, Vaxart partner on oral COVID-19 vaccine, $25M upfront plus $5M equity investment
Licensing deal, infectious disease, vaccine, milestone payments, equity investment - Read more

Kelonia Therapeutics, Johnson & Johnson collaborate on in vivo CAR-T therapies using iGPS platform
Research collaboration, cell therapy, gene therapy, oncology - Read more

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AstraZeneca's Imfinzi (durvalumab) reduces death risk by 22% in Ph3 gastric and gastroesophageal junction cancer trial
Antibody, cancer, monoclonal antibody, gastric cancer, perioperative therapy, combination therapy - Read more

Novo Nordisk presents Ph3 data showing oral Wegovy (semaglutide) reduces cardiovascular risk factors in obesity
Small molecule, metabolic, GLP-1 receptor agonist, obesity, cardiovascular risk factors - Read more

Centessa's ORX750 orexin receptor 2 agonist shows promise in Ph2a narcolepsy and idiopathic hypersomnia trial
Small molecule, neurological, orexin receptor agonist, narcolepsy, sleep disorders - Read more

Braveheart Bio launches with $185M to take on Bristol Myers Squibb’s heart drug in hypertrophic cardiomyopathy
Cardiovascular, small molecule, clinical-stage, hypertrophic cardiomyopathy - Read more

Amgen touts booming biosimilars sales, says U.S. market thriving amid FDA, RFK Jr. push to ease approval standards
Biosimilar, cardiovascular, strategic, financial - Read more

Madrigal Pharmaceuticals' Rezdiffra MASH treatment hits $287M Q3 sales, welcomes Novo's Wegovy competition
Small molecule, metabolic disease, competitive, revenue impact - Read more

Teva Pharmaceuticals reports 11th consecutive quarterly growth driven by innovative drug portfolio generating $830M sales
Small molecule, neurological, strategic, revenue impact - Read more

Evommune raises $150M IPO, developing drugs for immune conditions like hives and dermatitis
Autoimmune, small molecule, dermatology, clinical-stage - Read more

LambdaVision raises $7M Seed funding for protein-based artificial retina development
Retinal disease, protein-based therapy, microgravity manufacturing, preclinical - Read more

Hepta Bio raises $6.7M seed funding for blood-based liver disease diagnostics
Liver disease, blood-based diagnostics, biomarker discovery, MASH - Read more [Paywall]

MoonLake raises $75M follow-on funding, advancing sonelokimab for inflammatory diseases
Autoimmune, antibody, inflammatory diseases, clinical-stage - Read more

AstraZeneca invests additional $136M in Chinese inhalants plant, bringing total Qingdao investment to $886M
Inhalants, respiratory disease, strategic, major transaction, operational - Read more

Amgen advances MariTide to Phase III obesity trials amid Pfizer-Novo bidding war for Metsera
Antibody-peptide conjugate, obesity, strategic, competitive - Read more

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FDA rejects Biohaven's troriluzole (glutamate modulator) for spinocerebellar ataxia, company cuts R&D spending 60%
Small molecule, neurological, glutamate modulator, spinocerebellar ataxia - Read more

Amgen halts bemarituzumab Ph1b/3 trial for advanced gastric cancer due to inadequate efficacy
Antibody, cancer, monoclonal antibody, gastric cancer, FGFR2b target, combination therapy - Read more

Novo Nordisk CEO calls diabetes-obesity turnaround a 'marathon' after disappointing Q3 earnings performance
GLP-1 agonist, diabetes, obesity, financial, competitive, strategic - Read more

Charles River cuts costs, divests 7% of business amid continued revenue decline
CRO services, strategic, cost reduction, operational - Read more

Novo Nordisk abandons oncology, early MASH programs in $1.4B restructuring cutting 9,000 jobs
Cell therapy, oncology, strategic, cost reduction, operational - Read more

FTC warns Novo Nordisk's Metsera acquisition bid may circumvent required antitrust premarket review process
GLP-1 agonist, obesity, strategic, major transaction, competitive, regulatory - Read more

Delaware judge denies Pfizer's request to block Novo Nordisk's competing bid for Metsera biotech
Obesity therapeutics, strategic, major transaction, competitive - Read more

Supernus pauses new Parkinson's pump Onapgo patient starts due to overwhelming demand, supplier constraints
Small molecule, neurological, operational, supply chain - Read more

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